The same ‘marker’ molecule was also used as an antibody, targeting Gamma H2AX and delivering radiotherapy to breast cancer cells containing a large amount of this protein. This method works by identifying DNA damage and contributing to it, until the cells whither and die. Essentially, this technique can be used to scan the body for DNA damage and target such areas, ensuring that cancer cells cannot reach malignancy. If larger studies confirm the findings of this research, we may have a new method of detecting pre-cancerous cells, giving radiotherapy and monitoring the effectiveness of treatment – three major wellness benefits in just one molecule.
The scientists, who undertook the study at Oxford University’s Gray Institute for Radiation Oncology and Biology, were conservative in speaking of the results. Though they admitted their hope that this early research will allow them to one day perform full DNA scans of the body and detect cancer at its earliest stage, they were sure to highlight the need for larger studies to confirm the usefulness of this technique. However, spokesperson for Cancer Research UK Dr Julie Sharp expressed her excitement that working with this key molecule could provide valuable new directions for cancer research.
The discovery of such a valuable multipurpose molecule could indeed mean major advances in treatment, especially at the pre-cancerous stage. This could save many patients from the ravages of later treatments and mean excellent news for their wellbeing. With the increased Cancer Research funding now flowing into this project, we are entitled to feel a sense of optimism about this new direction.