Women who get chemotherapy risk early menopause, which makes it hard to conceive. A clinical trial of the drug Goserelin had positive results for women who still wanted to have children after their treatment.
Patients in trial done by the Cleveland Clinic all had early stage hormone receptor-negative breast cancer. The Goserelin was given to women as a shot every month before they went though their chemo treatments.
The drug shut down the ovaries during treatment, helping preserve their function down the road.
“The results found that our intervention was able to improve measures of ovarian function,” said Dr. Halle Moore with the Cleveland Clinic. “In addition we saw more pregnancies and more children being born in the group that received the intervention.”
More than 200 women between 25 and 45 years old participated in the trial. The study showed women who received the shot were less likely to have ovarian failure two years later. The drug also had another beneficial effect in those patients.
“We found that the women who received the Goserelin actually had fewer recurrences of their breast cancer and appeared to do better in overall survival as well,” said Dr. Moore.
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