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aurothioglucose
Pharmacy Author:
Annette (Gbemudu) Ogbru, PharmD, MBA
Annette (Gbemudu) Ogbru, PharmD, MBA
Dr. Gbemudu received her B.S. in Biochemistry from Nova Southeastern University, her PharmD degree from University of Maryland, and MBA degree from University of Baltimore. She completed a one year post-doctoral fellowship with Rutgers University and Bristol Myers Squibb.
Medical and Pharmacy Editor:
William C. Shiel Jr., MD, FACP, FACR
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
GENERIC NAME: aurothioglucose (This drug is discontinued in
the US)3h>
BRAND NAME: Solganal
DRUG CLASS AND MECHANISM: Aurothioglucose is a
gold-containing chemical (salt) used for treating
rheumatoid
arthritis. Other gold salts available include injectable
gold sodium
thiomalate (Myochrysine), and capsules,
auranofin
(Ridaura). It is not well understood exactly how gold salts work. In patients
with inflammatory
arthritis, such as adult and
juvenile
rheumatoid arthritis, gold salts can decrease the inflammation of the joint
lining. This effect prevents the inflammation from destroying the bone and
cartilage surrounding the joints and prevents or slows the development of
deformities of the joints. Because of their ability to prevent deformities, gold
salts are referred to as disease modifying anti-rheumatic drugs (DMARDs). DMARDs
like aurothioglucose may take weeks to months to become effective.
PRESCRIPTION: Yes
GENERIC AVAILABLE: No
PREPARATIONS: Injectable suspension: 50 mg/ml.
STORAGE: Aurothioglucose should be stored at room
temperature between 59 F and 86 F (15 C-30 C) away from light and moisture and
should not be frozen.
PRESCRIBED FOR: Aurothioglucose is used in the treatment of
active, progressive, or destructive forms of inflammatory arthritis, such as
adult and juvenile rheumatoid arthritis. Off label (non-FDA approved) uses
include Felty’s
Syndrome (a rare disorder that includes rheumatoid arthritis, a swollen
spleen, and
decreased white blood cell count) and
psoriatic
arthritis.
Medically Reviewed by a Doctor on 10/8/2014
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