Introduction of Medicines information

As medicines are a crucial part of medical treatment, it is important to have a good understanding of them.

How can you get medicines?

Some medicines are available from pharmacists or supermarkets, while others require a prescription from your GP or another healthcare professional.

The availability of medicines depends on the level of supervision experts believe is necessary before you use a particular medicine.

Under laws governing the supply of medicines, you can obtain medicine under three categories:

  • prescription-only medicines 
  • pharmacy medicines
  • general sales list medicines

These are explained in more detail below.

Prescription-only medicines

Prescription-only medicines (POMs) need a prescription issued by a GP or other suitably qualified healthcare professional. 

You then take the prescription to a pharmacy or a dispensing GP surgery to collect your medicine.

Pharmacy medicines

Pharmacy medicines (P) are available from a pharmacy without a prescription, but under the supervision of a pharmacist. You will need to ask staff at the pharmacy for this type of medicine because it is kept ‘behind the counter’ and is not available on the pharmacy shelves.

The pharmacist will check the medicine is appropriate for you and your health problem. They will ask you questions to ensure there is no reason why you should not use the medicine.

General sales list medicines

General sales list (GSL) medicines can be bought from pharmacies, supermarkets and other retail outlets without the supervision of a pharmacist. These are sometimes referred to as ‘over-the-counter’ (OTC) medicines.

OTC medicines include those that treat minor, self-limiting complaints, which people may feel are not serious enough to see their GP or pharmacist about.

Can medicines change their status?

New medicines tend to be licensed in the POM category so that healthcare professionals can supervise their use during the first few years that they are available.

If a medicine proves safe in large numbers of patients over several years, the regulatory agency may consider changing its status from POM to P. If it continues to be safe for another few years, a switch to GSL status may be considered so it can be sold directly from retail outlets.

If a medicine switches from POM to P or from P to GSL, the active ingredient remains exactly the same. This means the medicine is just as effective as when it had to be prescribed by a qualified prescriber.

It also means there is the same risk of side effects if you take too high a dose or do not follow instructions on the label. Therefore, it is important you follow the instructions carefully.

How are medicines developed?

In the UK, before any medicine can be used to treat people, it has to be licensed. Licences are only granted if high standards of safety and quality are met throughout the development process and the product works for the purpose intended.

In the UK, licenses can only be granted by the Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMA).

Potential medicines are first thoroughly researched using tissue culture, computer analysis techniques and animal testing.

If strict standards of safety and effectiveness are met, clinical trials involving humans can then be used. If a medicine passes all the phases of clinical trials, it can be licensed for wider use.

The whole process from discovery to licensing can take around 10-15 years.

Read more about licensing medicines.

How are medicines regulated?

No medicine is completely risk free, but attempts are made by the MHRA and EMA to ensure any medicine approved for widespread use is as safe as possible.

As well as a strictly monitored development process, medicines continue to be carefully regulated after they have been granted a license. This involves checking for problems, such as reports of previously unknown side effects.

In rare cases, medicines may be withdrawn if there are significant safety concerns or if the risks of the medicines outweigh potential benefits.

You can help regulate the safety of medicines by reporting symptoms you experience to the Yellow Card scheme.

The Yellow Card Scheme is a special reporting system for possible adverse effects of medicines. If you, or the healthcare professional treating you, think a medicine may have caused a potentially concerning effect, a report can be filed so problems can be spotted more easily.

Read more about medicine safety and regulation.

Why do the same medicines sometimes have different names?

Many medicines have at least two different names – a brand name and a ‘generic’ name.

The brand name is usually what the medicine is called by the company that first discovered and developed it. The generic name is the name of the active ingredient in the medicine that makes it work.

Initially (for a few years), the company that developed the medicine is the only one that can sell it, which means they can choose the price. To make a profit from the very costly development process, this usually means the medicine is very expensive at this point.

Generic copies are allowed to be made once this period ends. Generic medicines are usually as effective as the brand-name medicine because they contain the same active ingredients.

Generic medicines are used more often for treatment, because they are as effective as the original medicine, but cost far less.

Read more about generic and brand-name medicines.

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