Good Dental Hygiene Could Help Prevent Rheumatoid Arthritis, Say Scientists

Rheumatoid arthritis is an autoimmune condition – where your immune system attacks your own body – that causes swelling in the joints of the body, especially around the hands, feet and wrists.

So where does brushing your teeth fit in? According to US researchers, there is a link between the bacterium that causes gum disease, and how early the arthritis develops and how severe it is.

Scientists at the University of Louisville’s School of Dentistry in Kentucky discovered that gum disease produces a unique enzyme, which ‘enhances’ collagen-induced arthritis – a type of arthritis similar to rheumatoid arthritis.

The enzyme – called peptidylarginine deiminanse (PAD) – then changes proteins in the body into a different protein called citrulline. The body identifies citrulline as an intruder and then attacks it. For people who have rheumatoid arthritis or those who are prone to it, this means chronic inflammation.

 

Hard To Heal Injuries

It’s possible to think you have an injury — such as a sprained ankle that doesn’t seem to heal — when the symptoms are actually due to RA.

This is more common in younger people, says Lisa A. Mandl, M.D., M.P.H., assistant attending rheumatologist at Hospital for Special Surgery in New York City.

One day a patient is playing soccer and the next day her knee is swollen, she says. “I have seen people who have had two arthroscopic surgeries and extensive physical therapy in their knee and they have rheumatoid arthritis.”

Numbness Or Tingling In The Hands

One symptom of rheumatoid arthritis is carpal tunnel syndrome, which is marked by tingling in the wrist and hands. Dr. Mandl says the sensation is similar to the feeling you get when you hit your funny bone.

What happens is that the swelling in the arm compresses the nerves going into the hands. The sensation is often worse at night.

If you go to a doctor with these symptoms and don’t have (or tell him or her about) other RA symptoms, you may be diagnosed only with carpal tunnel syndrome.

 

Foot Trouble

One area in which people often have RA-related pain or inflammation is the forefoot.

Women often stop wearing heels and head to a podiatrist due to the pain.

Some people with RA may also develop pain in the heel because of plantar fasciitis, a common foot disorder caused by swelling of the tissue at the bottom of the foot, near the heel.

 

Eye Problems

People with RA are also at risk for Sjogrens syndrome, an autoimmune disorder that can cause dryness of the eyes, mouth, nose, throat, or skin due to inflammation that stops glands from releasing moisture, says Dr. Mandl.

This can happen even in the early stages of RA, but it’s unlikely to be the only symptom.

Most people with dry eyes head to an eye doctor to find out the cause, but Dr. Mandl recommends telling your doctor — even an eye doctor or other specialist — about additional symptoms you’re having in any part of the body.

Pairs Of Achy Joints

One of the most predominant symptoms of rheumatoid arthritis is aching in the joints. People often think their pain is due to overexertion or osteoarthritis, the type of arthritis common in old age.

This achiness can also be misdiagnosed as fibromyalgia or chronic fatigue syndrome (fatigue is another symptom of RA).

RA joint pain is not fleeting; it usually lasts longer than a week. It can also be symmetrical, meaning both hands, feet, knees, or ankles will be affected at the same time.

Morning Stiffness

Another characteristic of rheumatoid arthritis is stiffness in the joints in the morning.

Again, this is also a common problem in osteoarthritis, which can cause pain after long periods of inactivity, like sleeping.

The difference between the two is that osteoarthritis pain usually subsides in about a half hour. Stiffness from rheumatoid arthritis will last much longer, possibly for a good chunk of the day.

The right kind of exercise can help alleviate stiffness for people with RA and osteoarthritis pain.

Locked Joints

People with RA can sometimes experience locked joints, particularly in the knees and elbows. This happens because there’s so much swelling of the tendons around the joint, the joint cannot bend. It can lead to cysts behind the knee that can puff out and inhibit motion.

The symptom can be mistaken for a meniscus tear, a knee joint injury that’s common in sports, and which can also lead to cysts.

 

Nodules

These are firm lumps that grow under the skin near the affected joints. They often appear at the back of the elbows, and sometimes people get them in the eyes.

They’re more common in people who have advanced rheumatoid arthritis, but occasionally show up earlier, says Dr. Mandl.

The nodules can at times mimic gout, another form of arthritis.

Previously studies, reported the Mail Online, reveal that gum disease is at least twice “more prevalent in rheumatoid arthritis patients.”

Led by Jan Potempa and his team, they also studied another oral bacterium for the same affect, but learned it did not produce the same effects.

 

SYMPTOMS:

 

Pain

This is usually a throbbing and aching sort of pain. Often worse in the mornings and after you have been sitting still for a while. Pain is often felt while you are resting, not after activity.

 

Stiffness

Joints affected by rheumatoid arthritis can feel stiff, especially in the morning. Morning stiffness associated with a kind of arthritis called osteoarthritis usually wears off within 30 minutes of getting up. However, rheumatoid arthritis morning stiffness usually lasts longer than half an hour.

 

Warmth and redness

The lining of the affected joint becomes inflamed, causing the joints to swell, and become hot, tender to touch and painful.

 

Rheumatoid arthritis can also cause inflammation around the joints, such as rheumatoid nodules, and in other parts of your body. The condition can also cause inflammation of your tear glands, salivary glands, the lining of your heart and lungs, and your blood vessels.

 

“Taken together, our results suggest that bacterial PAD may constitute the mechanistic link between P. gingivalis periodontal infection and rheumatoid arthritis, but this ground-breaking conclusion will need to be verified with further research,” he said.

 

Potempa said he is hopeful these findings will shed new light on the treatment and prevention of rheumatoid arthritis.

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